Jen Bohon, Ph.D.

Faculty Appointments

Center for Proteomics and Bioinformatics:
Assistant Professor

Center for Synchrotron Biosciences

Academic History

1996B.A., Biology, Johns Hopkins University, Baltimore, MD
2004Ph.D.,Physiology & Biophysics, Stony Brook University, Stony Brook, NY
2004-2005Post Doctoral Research Associate, Biophysics, Brookhaven National Laboratory, Upton, NY
2005-2009Post Doctoral Fellow, Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH

Positions and Employment

1996-2004Research Assistant, Stony Brook University, Stony Brook, NY
2005-Beamline Scientist, Center for Synchrotron Biosciences, Brookhaven National Laboratory, Upton, NY
2009-2010Senior Research Associate, Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH
2010-2014Instructor, Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH
2014-currentAssistant Professor, Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH

Research Interests

My research interests focus on two overall themes: integration of multiple structural biological techniques to develop a comprehensive understanding of functional macromolecular complexes, and development of instrumentation to improve the tools available for such studies. Techniques of interest include synchrotron protein footprinting, x-ray absorption spectroscopy, small-angle x-ray scattering, x-ray crystallography, infrared microspectroscopy, biochemical kinetic studies of enzymes and computational modeling.

A new synchrotron facility, NSLS-II , has recently been completed at Brookhaven National Laboratory (Fall 2014) to replace the former light source. Because the facility has just opened, many of the capabilities that will eventually be provided at this world-class light source are not yet available. In preparation for this transition period, the Center for Synchrotron Biosciences team has developed programs in x-ray footprinting and x-ray spectroscopy at the Advanced Light Source and the Stanford Synchrotron Radiation Light Source, respectively. Our team is simultaneously working to develop and construct new beamlines to extend and expand the scientific programs and services currently provided to take advantage of the new facility at NSLS-II. As part of this effort, I am leading the effort to develop a world-leading program in x-ray footprinting at the NSF-CWRU funded beamline XFP (X-ray Footprinting for In Vitro and In Vivo Structural Studies of Biological Macromolecules) currently being constructed at NSLS-II. Please see the Center for Synchrotron Biosciences website for details.

My Publications