Sudipto Saha, Ph.D.

Position Center for Proteomics and Bioinformatics: Post Doctoral Fellow

Expertise

Interaction Proteomics

Research Interests

Dr. Saha received his Ph.D in Bioinformatics from Jawaharlal Nehru University, New Delhi, India in 2007. He previously worked on computer aided prediction of vaccine candidate(s) based on B-Cell epitopes at the Institute of Microbial Technology, Chandigarh, India and in a Clinical Proteomic Technology Assessment for Cancer (CPTAC) program for biomarker discovery in breast cancer at Indiana University-Purdue University, Indianapolis, IN. Presently, he is working as Postdoctoral Fellow in Rob Ewing's lab.

His research involves:

1) Analyzing protein-protein interactions from Affinity Purification - Mass Spectrometry (AP-MS) data and investigating scores such as Normal Spectral Abundance Factor (NSAF) and Z-score that prioritize the interacting proteins specific to a bait protein. Furthermore he is working on global analysis of large scale human protein-protein interactions to identify not only Bait-Prey interactions, but also Bait-Bait and Prey-Prey interactions.

2) Developing data driven methods for predicting the outcome of baits using AP-MS and Yeast two hybrid (Y2H) techniques.

3) Integrating data from different sources such as transcriptomics, motif based sequence information and interaction proteomics to understand biological pathways (for example Wnt signaling).

Contact Info